| Abstract:Objective To evaluate the clinical efficacy of traditional Chinese medicine decoction in the treatment of secretory otitis media by network meta-analysis based on Bayesian framework. Methods PubMed, Web of Science, Embase, the Cochrane Library, CNKI, Wanfang Data, VIP, and China Biology Medicine Disc were searched for studies on Chinese medicine decoction in the treatment of secretory otitis media from the inception to July 2023. The Cochrane Collaboration’s tool for assessing the risk of bias was used for quality assessment. Stata 17.0 and GeMTC 0.14.3 software were used for data analysis. Results A total of 19 studies were included, with a sample size of 2 069 cases, involving nine kinds of Chinese medicine decoctions. The results of network meta-analysis showed that the total clinical effective rate of Jiawei Qingzhen Decoction (OR=0.27, 95%CI： 0.07-0.73), Shenling Baizhu Powder (OR=0.29, 95%CI： 0.11-0.74), Erzhang Decoction (OR=0.17, 95%CI： 0.08-0.35), Erchen Decoction (OR=0.29, 95%CI： 0.11-0.69), Jianpi Tongqiao Prescription (OR=0.32, 95%CI： 0.12-0.78), Jingfang Baidu Powder (OR=0.17, 95%CI： 0.08-0.35), Longdan Xiegan Decoction (OR=0.23, 95%CI： 0.11-0.48), Shufeng Xuanfei Tongqiao Decoction (OR=0.21, 95%CI： 0.08-0.60), Xuanfei Tongqiao Decoction (OR=0.15, 95%CI： 0.04-0.41) combined with conventional western medi- cine respectively were higher than those of conventional western medicine alone. The result of rank probability graph showed that Xuanfei Tongqiao Decoction had the best effect. Conclusion Chinese medicine decoction can improve the total effective rate in the treatment of secretory otitis media, among which Xuanfei Tongqiao Decoction has the best efficacy, but a larger sample and higher quality randomized controlled clinical |
