| 李艳丽,徐海燕,高静.基于数据挖掘的《中华医典》中吹喉方外治喉痹用药规律分析[J].中国医药导报,2024,21(1):10-14 |
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| 基于数据挖掘的《中华医典》中吹喉方外治喉痹用药规律分析 |
| Analysis of the law of blowing throat formula for external treatment of laryngeal arthralgia in Chinese Medical Code based on data mining |
| 收稿日期：2023-07-12 |
| DOI：10.20047/j.issn1673-7210.2024.01.02 |
| 关键词: 吹喉方 喉痹 用药规律 数据挖掘 |
| Key Words: |
| 基金项目:国家自然科学基金资助项目（82060696）；“十四五”新疆维吾尔自治区高等学校重点学科（新教函〔2022〕112号）。 |
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| 摘要:目的 利用数据挖掘技术，分析《中华医典》中吹喉方治疗喉痹的组方用药规律。 方法 搜集第五版《中华医典》中吹喉方治疗喉痹的相关文献，运用Excel、SPSS、Gephi软件进行中药频次、功效、性味、归经、关联规则、复杂网络、聚类等统计分析。 结果 共纳入481首吹喉方，涉及中药259味，其中频次≥40的药物有21味，以冰片、硼砂、白矾、青黛为多，清热药使用最多，药性多寒凉，药味以辛、苦、咸为主，多归肺、肝、心、胃经。关联规则分析得到12个关联方，以僵蚕+冰片-硼砂置信度最高，硼砂-冰片支持度最高，二者为481首方中最核心药物；聚类分析得到4个聚类方。 结论 吹药多具消炎抗菌、镇痛等药理作用，喉痹的发生多因火热、痰邪，以清热利咽、涤痰消肿为吹喉方外治关键，在治疗上外治喉痹亦遵循审病求因、辨证论治的治疗原则。 |
| Abstract:Objective To use data mining technology and to analyze the rule of combination of prescription and medication for laryngeal arthralgia in Chinese Medical Code. Methods The literatures on the treatment of laryngeal arthralgia in the fifth edition of Chinese Medical Code were collected and analyzed by Excel, SPSS, and Gephi software, such as frequency, efficacy, sex, taste, normalization, association rules, complex network, and clustering. Results A total of 481 blowing throat formula were included, involving 259 traditional Chinese medicine flavors, of which 21 were drugs with frequency ≥40, mainly borneol, borax, alum, and Qingdai. The most commonly used drugs for clearing heat were drugs with cold and cold properties, and their tastes were mainly xin, bitter and salty, mostly attributed to lung, liver, heart and stomach channels. A total of 12 related parties were obtained by association rule analysis, and the confidence of bombyx mori + borneol and borneol was the highest, and the support of borneol and borneol was the highest. Four clustering methods were obtained by cluster analysis. Conclusion Blowing medicine has anti-inflammatory, antibacterial, analgesic, and other pharmacological effects, the occurrence of throat impediment is mostly due to fire, phlegm evil, to clear heat and soothe the throat, remove phlegm, and reduce swelling as the key to the external treatment of throat impediment, in the treatment of external treatment also follow the principle of examining the disease and seeking the cause, syndrome differentiation. |
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