| 闫茹玉,胡学敬,张晓阳,王春宁.郭氏益气通脉汤联合养心康复操治疗经皮冠状动脉介入治疗术后气阴两虚兼瘀阻经络证心绞痛的临床效果[J].中国医药导报,2024,21(1):126-130 |
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| 郭氏益气通脉汤联合养心康复操治疗经皮冠状动脉介入治疗术后气阴两虚兼瘀阻经络证心绞痛的临床效果 |
| Clinical efficacy on Guoshi Yiqi Tongmai Decoction combined with yang- xin kangfu gymnastics in treating angina pectoris of qi yin deficiency combined with stasis obstructing meridian after percutaneous coronary intervention |
| 收稿日期：2023-07-14 |
| DOI：10.20047/j.issn1673-7210.2024.01.27 |
| 关键词: 经皮冠状动脉介入治疗 心绞痛 郭氏益气通脉汤 养心康复操 疗效 |
| Key Words: |
| 基金项目:河北省中医药管理局中医药类科学研究课题计划项目（2023285） |
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| 摘要:目的 探讨郭氏益气通脉汤联合养心康复操治疗经皮冠状动脉介入治疗（PCI）术后心绞痛的临床效果。方法 选取河北省衡水市中医院2022年7月至2023年4月收治的60例PCI术后心绞痛患者，按照随机数字表法将其分为对照组和观察组，各30例。其中对照组采用常规西药治疗，在对照组的基础上，观察组采用郭氏益气通脉汤和养心康复操治疗，两组均治疗2个月。评价两组临床疗效，比较两组治疗前后中医症状积分、西雅图心绞痛评分、左室射血分数（LVEF）、每搏输出量（SV）及血脂指标[总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）]。记录治疗期间心血管不良事件的发生情况。 结果 观察组临床疗效优于对照组（P＜0.05）。治疗后，两组中医症状评分均较治疗前降低，且观察组低于对照组（P＜0.05）。治疗后，两组西雅图心绞痛评分较治疗前升高，且观察组高于对照组（P＜0.05）。治疗后，两组LVEF、SV较治疗前升高，且观察组高于对照组（P＜0.05）。治疗后，两组HDL水平较治疗前升高，TG、TC及LDL水平较治疗前降低，且观察组HDL水平高于对照组，TG、TC及LDL水平低于对照组（P＜0.05）。两组心血管不良事件发生率比较，差异无统计学意义（P＞0.05）。结论 郭氏益气通脉汤联合养心康复操治疗PCI术后心绞痛的临床疗效较好，有助于临床症状的减轻和心功能的改善，调节血脂水平，且安全性较好。 |
| Abstract:Objective To investigate the clinical efficacy of Guoshi Yiqi Tongmai Decoction combined with yangxin kangfu gymnastics in the treatment of angina pectoris after percutaneous coronary intervention（PCI）. Methods Sixty patients with postoperative angina pectoris admitted to Hengshui Traditional Chinese Medicine Hospital from July 2022 to April 2023 were divided into observation group and control group according to the random number table method, with 30 cases in each group. The control group received conventional western medicine treatment. On the basis of the control group, the observation group received Guoshi Yiqi Tongmai Decoction and yangxin kangfu gymnastics treatment. Both groups were treated for two months. The clinical efficacy of two groups was evaluated, and the traditional Chinese medicine symptom scores, Seattle angina score, left ventricular ejection fraction (LVEF), stroke output (SV), and blood lipid indicators （total cholesterol[TC), triacylglycerol[TG], high density lipoprotein [HDL], and low density lipoprotein[LDL]) were compared before and after treatment. The occurrence of cardiovascular adverse events during treatment was recorded. Results The clinical efficacy of the observation group was better than that of the control group (P＜0.05). After treatment, the traditional Chinese medicine symptom scores of both groups were lower than before treatment, and the observation group was lower than the control group (P＜0.05). After treatment, the Seattle angina scores in both groups were higher than before treatment, and the observation group was higher than the control group (P＜0.05). After treatment, LVEF and SV in both groups were higher than before treatment, and the observation group was higher than the control group (P＜0.05). After treatment, HDL-C levels in both groups were higher than before treatment, TG, TC, and LDL-C levels were lower than before treatment, and HDL-C levels in observation group were higher than control group, TG, TC, and LDL-C levels were lower than control group (P＜0.05). There was no significant difference in the incidence of cardiovascular adverse events between the two groups (P＞0.05). Conclusion Guoshi Yiqi Tongmai Decoction combined with yangxin kangfu gymnastics in the treatment of angina pectoris after PCI is significant, which can significantly reduce the clinical symptoms, improve cardiac function and regulate blood lipid levels, and has good safty. |
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