| 杨睿,杨梓鸣,黄亚琴,朱丽芬,郭小霞.玉叶金花清热片治疗急性咽喉炎的临床效果[J].中国医药导报,2024,21(4):112-115 |
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| 玉叶金花清热片治疗急性咽喉炎的临床效果 |
| Clinical effect of Yuye Jinhua Qingre Tablets in treating acute laryngopharyngitis |
| 收稿日期： 修订日期：2023-03-24 |
| DOI：10.20047/j.issn1673-7210.2024.04.26 |
| 关键词: 玉叶金花清热片 急性咽喉炎 中西医结合疗法 抗生素 |
| Key Words: |
| 基金项目:广东省深圳市科技计划项目（201203233） |
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| 摘要:目的 探讨玉叶金花清热片治疗急性咽喉炎的临床效果。 方法 选择2022年9月至12月深圳市前海蛇口自贸区医院耳鼻喉科就诊的急性咽喉炎患者100例，采用随机数字表法将其分为对照组和观察组，各50例。对照组给予头孢呋辛酯片治疗，观察组在对照组的基础上给予玉叶金花清热片治疗，两组均治疗5 d。比较两组临床疗效；比较两组治疗前后咽痛、干痒咳嗽、咽部充血评分；比较两组治疗前后咽痛、干痒咳嗽、咽部充血消退时间；比较两组治疗前后C反应蛋白（CRP）、白细胞计数（WBC）及中性粒细胞计数水平；观察治疗期间不良反应发生情况。 结果 观察组临床疗效优于对照组（P＜0.05）。治疗后，两组咽痛、干痒咳嗽、咽部充血评分及CRP、WBC、中性粒细胞计数低于治疗前，且观察组低于对照组（P＜0.05）。观察组咽痛、干痒咳嗽、咽部充血消退时间短于对照组（P＜0.05）。两组均未出现胃肠道不适及肝肾功能异常等不良反应。 结论 玉叶金花清热片治疗急性咽喉炎效果显著，可广泛使用。 |
| Abstract:Objective To investigate the clinical effect of Yuye Jinhua Qingre Tablets in treating acute laryngopharyngitis. Methods A total of 100 patients with acute laryngopharyngitis were selected from the Department of Otolaryngology, Shenzhen Qianhai Shekou Free Trade Zone Hospital from September to December 2022 were selected. They were divided into control group and observation group by random number table method, with 50 cases in each group. The control group was treated with Cefuroxime Axetil Tablets, and observation group was treated with Yuye Jinhua Qingre Tablets on the basis of control group. Both groups were treated for 5 d. The clinical effect of two groups was compared; the scores of pharyngeal pain, dry itching cough, and pharyngeal congestion before and after treatment were compared between two groups; the regression time of pharyngeal pain, dry itching cough, and pharyngeal congestion before and after treatment were compared between two groups; the levels of C-reactive protein (CRP), white blood cell count (WBC), and neutrophil count before and after treatment were compared between two groups; the occurrence of adverse reactions during treatment was observed. Results The clinical effect of observation group was better than that of control group (P＜0.05). After treatment, the scores of pharyngeal pain, dry itching cough, and pharyngeal congestion, and CRP, WBC, and neutrophil count in two groups were lower than those before treatment, and observation group was lower than control group (P＜0.05). The regression time of pharyngeal pain, dry itching cough, and pharyngeal congestion in observation group were shorter than those in control group (P＜0.05). There was no gastrointestinal discomfort or adverse reactions of liver and kidney in both groups. Conclusion Yuye Jinhua Qingre Tablets is effective in treating acute laryngopharyngitis and can be widely used. |
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