| 胡惠惠,刘燕观,李雨阳.通窍活血汤联合通督调神针法治疗气虚血瘀型缺血性脑卒中后偏瘫的临床研究[J].中国医药导报,2024,21(4):148-152 |
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| 通窍活血汤联合通督调神针法治疗气虚血瘀型缺血性脑卒中后偏瘫的临床研究 |
| Clinical study on Tongqiao Huoxue Decoction combined with tongdu tiao- shen acupuncture in treating hemiplegia after ischemic stroke of qi deficiency and blood stasis type |
| 收稿日期： 修订日期：2023-08-17 |
| DOI：10.20047/j.issn1673-7210.2024.04.34 |
| 关键词: 缺血性脑卒中 偏瘫 通窍活血汤 通督调神针法 临床疗效 |
| Key Words: |
| 基金项目:陕西省中医药管理局项目（2021-GJ-LC025）；陕西省榆林市科协青年人才托举计划项目（20220463） |
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| 摘要:目的 探讨通窍活血汤联合通督调神针法治疗气虚血瘀型缺血性脑卒中后偏瘫的临床效果。 方法 选取2021年1月至2022年7月陕西省榆林市中医医院收治136例缺血性脑卒中后偏瘫患者为研究对象，电脑随机抽签法将其分为三组。汤药组（45例）以常规治疗+通窍活血汤治疗，针灸组（45例）以常规治疗+通督调神针法治疗，联合组（46例）以常规治疗+通窍活血汤+通督调神针法治疗，14 d为1个疗程，治疗3个疗程后比较三组中医症候积分、临床疗效、神经功能指标、治疗安全性。 结果 治疗后，三组中医症候积分均较治疗前降低，且联合组低于汤药组、针灸组（P＜0.05）。联合组临床疗效优于汤药组、针刺组（P＜0.05）。治疗后，三组泛素羧基末端水解酶1、微管相关蛋白、神经元特异性烯醇化酶水平均较治疗前降低，且联合组低于汤药组、针灸组（P＜0.05）。治疗期间三组不良反应发生率比较，差异无统计学意义（P＞0.05）。 结论 通窍活血汤联合通督调神针法治疗缺血性脑卒中后偏瘫效果显著，能改善中医证候，改善神经功能指标，有较好的安全性。 |
| Abstract:Objective To explore the clinical effect of Tongqiao Huoxue Decoction combined with tongdu tiaoshen acupuncture on hemiplegia after ischemic stroke of qi deficiency and blood stasis type. Methods A total of 136 patients with hemiplegia after ischemic stroke admitted to Yulin Hospital of Traditional Chinese Medicine from January 2021 to July 2022 were selected as the subjects, and they were divided into three groups by computer drawing. The decoction group (45 cases) was treated with routine treatment+Tongqiao Huoxue Decoction, the acupuncture group (45 cases) was treated with routine treatment+tongdu tiaoshen acupuncture, and the combined group (46 cases) was treated with routine treatment+Tongqiao Huoxue Decoction+tongdu tiaoshen acupuncture. After three courses of treatment, the traditional Chinese medicine syndrome score, clinical efficacy, neurological function index, and treatment safety were compared among the three groups. Results After treatment, the traditional Chinese medicine symptom scores of the three groups were lower than those before treatment, and the combined group were lower than those of the decoction group and the acupuncture group (P＜0.05). The clinical efficacy of the combined group was better than that of the decoction group and acupuncture group (P＜0.05). After treatment, the levels of ubiquitin carboxyl terminal hydrolase 1, microtubule associated proteins, and neuron specific enolase in the three groups were lower than those before treatment, and the combined group were lower than those in the decoction group and the acupuncture group (P＜0.05). During the treatment period, there was no statistically significant difference in the incidence of adverse reactions among the three groups (P＞0.05). Conclusion The combination of Tongqiao Huoxue Decoction and tongdu tiaoshen acupuncture has significant effect on treating hemiplegia after ischemic stroke, which can improve traditional Chinese medicine symptoms, improve neurological function indicators, and have good safety. |
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