王薇,邱娟,沈恺.多发性骨髓瘤化疗患者自我调节疲乏对化疗耐受能力的影响[J].中国医药导报,2024,21(5):61-65 本文二维码信息
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多发性骨髓瘤化疗患者自我调节疲乏对化疗耐受能力的影响
Effect of self-regulatory fatigue on chemotherapy tolerance in patients with multiple myeloma
收稿日期:  修订日期:2023-05-10
DOI:10.20047/j.issn1673-7210.2024.05.15
关键词:  多发性骨髓瘤  化疗  化疗耐受能力  自我调节疲乏  癌症体验和效能  自我管理
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基金项目:四川省自然科学基金资助项目(2022NSFSC1463)
作者单位
王薇 四川大学护理学院 四川大学华西医院血液内科四川成都 610000 
邱娟 四川大学护理学院 四川大学华西医院血液内科四川成都 610000 
沈恺 四川大学护理学院 四川大学华西医院血液内科四川成都 610000 
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摘要:目的 了解多发性骨髓瘤(MM)化疗患者自我调节疲乏现状,分析其对患者化疗耐受能力的影响。 方法 采用便利抽样法,抽取2020年1月至2022年1月四川大学华西医院收治的105例MM患者为研究对象,采用自我调节疲乏量表(SRF-S)、癌症体验和效能量表(CEES)、癌症患者自我管理测评量表评估患者自我疲乏、癌症自我管理情况。观察MM化疗患者化疗耐受能力,分析MM化疗患者自我调疲乏对化疗耐受能力的影响。 结果 本研究共纳入105例MM患者,共发放问卷105份,有效回收100份,有效回收率为95.24%。100例MM患者SRF-S评分为(53.28±11.14)分;CEES量表的癌症体验评分为(46.63±12.82)分,控制效能评分为(35.47±7.51)分;平均自我管理评分为(157.54±20.93)分。化疗耐受能力差组SRF-S评分高于化疗耐受能力良好组,差异有统计学意义(P<0.05);经点二列相关性检验,SRF-S评分与MM化疗患者化疗耐受能力呈正相关(r>0,P<0.01)。结论 自我调节疲乏与MM化疗患者的化疗耐受能力存在明显相关性,护理人员可根据患者自我调节疲乏状况实施有效干预,提高化疗耐受能力。
Abstract:Objective To investigate the status quo of self-regulatory fatigue in patients with multiple myeloma (MM) chemotherapy, and to analyze its effect on chemotherapy tolerance. Methods A total of 105 MM patients admitted to West China Hospital of Sichuan University from January 2020 to January 2022 were selected by convenient sampling method. Self-regulated fatigue scale (SRF-S), cancer experience and efficacy scale (CEES) and cancer patient self-management assessment scale were used to evaluate patients’ self-fatigue and cancer self-management. The chemotherapy tolerance of MM patients and the effect of self-regulating fatigue on chemotherapy tolerance of MM patients were observed and analyzed. Results A total of 105 MM patients were included in this study. A total of 105 questionnaires were sent out, and 100 were effectively recovered, with an effective recovery rate of 95.24%. The SRF-S score of 100 MM patients was (53.28±11.14) points. The cancer experience score of CEES was (46.63±12.82) points, and the control efficacy score was (35.47±7.51) points. The average self-management score was (157.54±20.93) points. The SRF-S score of poor chemotherapy tolerance group was higher than that of good chemotherapy tolerance group, and the difference was statistically significant (P<0.05). By point two-column correlation test, SRF-S score was positively correlated with chemotherapy tolerance of MM patients (r>0, P<0.01). Conclusion There is a significant correlation between self-regulated fatigue and chemotherapy tolerance in MM patients. Nursing staff can implement effective intervention according to patients’ self-regulated fatigue status to improve chemotherapy tolerance.
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